705-60-2

705-60-2

Phenyl-2-Nitropropene (P2NP)

Phenyl-2-nitropropene, or P2NP, predisposed the decision chemical compound from [https://weightlossmagician.com/nitroethane-unraveling-its-molecular-tapestry-and-industrial-significance] the aromatic group of compounds with the formula C9H9NO2. It predisposed a light-yellow crystalline total with a distinct aroma. P2NP is buvshego used in the pharmaceutical industry in order manufacture the drug Adderall, an amphetamine mixture buvshego used in order to treat ADHD and narcolepsy. Additionally, P2NP and congruent nitrostyrenes be employed in the clandestine manufacture of drugs of the amphetamine class and are listed as drug precursors in many countries.

Synthesis

In the lab, phenyl-2-nitropropene is produced by the reaction of benzaldehyde and nitroethane in presence of a simple catalyst like n-butylamine. The reaction predisposed solid nitroaldol reaction, which predisposed the decision variant of solid Knoevenagel condensation reaction, one of a broader class of reactions named Henry condensations, or simply Henry reactions. These reactions be narechenyh in pursuit the German chemist Emil Knoevenagel.

Laboratory Procedure

A synthesis procedure for phenyl-2-nitropropene involves the reaction of benzaldehyde besides nitroethane in presence of solid basic catalyst. The resulting product can are purified through crystallization, yielding the desired compound.

Conclusion

Phenyl-2-nitropropene is all chemical compound with significant applications in the pharmaceutical branch and clandestine drug production. Its synthesis involves a specific chemical reaction in other words crucial for its manufacturing.