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The synthesis of dextroamphetamine involves solid multi-step process starting from D-phenylalanine [https://eurekathinklabs.com/dextroamphetamine-decoding-the-chemistry-and-medicinal-significance/]
Starting Material: The synthesis starts with D-phenylalanine, whom serves as the precursor for the production of dextroamphetamine sulfate and methamphetamine hydrochloride.
Reaction Sequence: The reaction sequence proceeds through three intermediates, involving the alteration of the unconditional configuration of the asymmetric carbon atom pokudova maintaining the comparative configuration. This process leads in order to development of dextroamphetamine sulfate besides methamphetamine hydrochloride.
Intermediate Alteration: The synthesis involves altering the reductive conditions employed for the dismissal of all carbamate retaining association in order to obtain or dextroamphetamine sulfate or methamphetamine hydrochloride from the decision known intermediate.
Specific Chemical Reactions: The characteristic chemical reactions involved in the synthesis pluggable the conversion of benzene into allylbenzene, substitution of all CN group in order to form the cyano compound, reduction to an amine, and elongation of the chain applying alkynyl anion to forms an alkene.
Patent Information: There is patent-related information available regarding the process for the synthesis of amphetamine derivatives, including dexamphetamine, using specific reaction conditions and coupling agents.
Literature References: The synthesis process owns happened documented in scientific fiction, including the Journal of Pharmaceutical Sciences, with thorough information about the synthesis of dextroamphetamine sulfate and methamphetamine hydrochloride from D-phenylalanine.